Merck Anti-AKR1C3 antibody, Mouse monoclonal

Anti-AKR1C3 antibody, Mouse monoclonal

clone NP6.G6.A6, purified from hybridoma cell culture

Quality Level

200

생물학적 소스

mouse

결합

unconjugated

항체 형태

purified immunoglobulin

antibody product type

primary antibodies

클론

NP6.G6.A6, monoclonal

form

buffered aqueous solution

분자량

antigen ~38 kDa

species reactivity

human

포장

antibody small pack of 25 μL

technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
microarray: suitable
western blot: 0.25-0.5 μg/mL using cytosolic fraction extract of A549 human lung carcinoma cell

동형

IgG1

UniProt 수납 번호

P42330

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... AKR1C3(8644)

Anti-AKR1C3 antibody, Mouse monoclonal (humanα - hydroxysteroid dehydrogenase, type 2,3; 17β- hydroxysteroid dehydrogenase, type 5) (mouse IgG1 isotype) is derived from the hybridoma NP6.G6. A6 produced by the fusion of mouse myeloma cells (SP20 cells) and splenocytes from BALB/c mice immunized with human AKR1C3 protein. Oxidoreduction of natural and foreign substrates is performed by three enzymes superfamilies, one of them being the AKRs (aldo-keto reductases) family. This family contains 114 proteins that are expressed in prokaryotes and eukaryotes and is divided into 14 subfamilies (AKR1-AKR14). The AKR1 family is the largest among the different fourteen families and contains the aldose reductases, aldehyde reductases, hydroxysteroid dehydrogenases, and steroid 5 β-reductases. AKR1Cs are expressed in many tissues.