Merck Monoclonal Anti-Proliferating Cell Nuclear Antigen antibody produced in mouse

Monoclonal Anti-Proliferating Cell Nuclear Antigen antibody produced in mouse

clone PC 10, ascites fluid

Monoclonal Anti-Proliferating Cell Nuclear Antigen, Anti-PCNA

Quality Level

200

생물학적 소스

mouse

결합

unconjugated

항체 형태

ascites fluid

antibody product type

primary antibodies

클론

PC 10, monoclonal

포함

15 mM sodium azide

species reactivity

rat, mouse
yeast, monkey, insect, human

포장

antibody small pack of 25 μL

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:3,000 using human tonsil sections
immunohistochemistry (frozen sections): suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
microarray: suitable
western blot: 1:3,000 using HS-68 human foreskin- cell extract

동형

IgG2a

UniProt 수납 번호

P04961
P12004

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... PCNA(5111)

PCNA (proliferating cell nuclear antigen) is a member of the structurally and functionally conserved family of DNA sliding clamps (β clamps). They exist as ring-shaped complexes- homotrimers in eukaryotes, having pseudohexameric symmetry. A monomer of PCNA is composed of two similar globular domains, connected by an interdomain connecting loop, which is a long, and probably a flexible loop. These monomers organize themselves in a head-to-tail manner to form a ring, which has an inner positively charged surface composed of α helices and an outer surface of β sheets.