Merck Kallikrein-11 human

Kallikrein-11 human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

Hippostasin, KLK11, PRSS20, TLSP, hK11

생물학적 소스

human

재조합

expressed in HEK 293 cells

태그

6-His tagged (C-terminus)

assay

≥95% (SDS-PAGE)

form

lyophilized

분자량

calculated mol wt 26.5 kDa
observed mol wt 35-45 kDa (DTT-reduced.Protein migrates due to glycosylation. Glu 19 is the predicted N-terminal.)

포장

pkg of 10 μg

UniProt 수납 번호

Q9UBX7

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... KLK11(11012)

Kallikrein 11 (KLK11) is also known as Hippostasin, Serine protease 20, Trypsin-like protease, PRSS20, TLSP, which belongs to the peptidase S1 family and Kallikrein subfamily. KLK11 contains one peptidase S1 domain. KLK11 is expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 μg/mL (at protein level). Kallikrein 11 /KLK11 is a possible multifunctional protease and efficiently cleaves ′bz-Phe-Arg-4-methylcoumaryl-7-amide′, a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. KLK11 cleaves synthetic peptides after arginine but not lysine residues.