Merck SILuMAb Mouse Stable-Isotope Labeled Monoclonal Antibody

SILu™MAb Mouse Stable-Isotope Labeled Monoclonal Antibody

from mouse, recombinant, expressed in CHO cells

Quality Level

200

생물학적 소스

mouse

재조합

expressed in CHO cells

antibody product type

primary antibodies

assay

≥90% (SDS-PAGE)

포장

vial of 100 μg

배송 상태

wet ice

저장 온도

−20°C

SILu™MAb Mouse is a recombinant, stable isotope-labeled, mouse monoclonal antibody which incorporates [13C6, 15N4]-Arginine and [13C6, 15N2]-Lysine. Expressed in CHO cells, SILu™MAb Mouse is designed to be used as a universal internal standard for bioanalysis of monoclonal murine antibodies in animal pharmacokinetics (PK) studies.

SILu™MAb Mouse is an IgG1 antibody with a kappa light chain. Because of overlap with common sequences in the Fc region with candidate murine antibodies, SILu™MAb Mouse provides universal utility, and thus, eliminates the need to produce candidate-specific internal standards.