Merck Anti-Dab-1 (C-terminal) from rabbit

Anti-Dab-1 (C-terminal) from rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

생물학적 소스

rabbit

Quality Level

200

결합

unconjugated

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

antigen ~80 kDa

species reactivity

human, mouse, rat

향상된 검증

recombinant expression
Learn more about Antibody Enhanced Validation

농도

~1 mg/mL

technique(s)

western blot: 2-4 μg/mL using HEK-293T cells expressing human DAB1
western blot: 2-4 μg/mL using mouse and rat brain extracts (S1 fraction)

UniProt 수납 번호

O75553

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... DAB1(1600)
mouse ... Dab1(13131)
rat ... Dab1(266729)

Disabled-1 is an intracellular adaptor protein that belongs to the Reelin signaling pathway. The amino terminus of Dab1 contains a phosphotyrosine-binding (PTB) domain. The domain interacts with NPXY sequences within the cytoplasmic regions of several membrane-bound proteins including lipoprotein receptors and amyloid precursor protein (APP) family.