Merck Anti-PREB antibody produced in rabbit

Anti-PREB antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Anti-Mammalian guanine nucleotide exchange factor mSec12, Anti-Prolactin regulatory element-binding protein

The gene PREB (prolactin regulatory element binding) is also referred to as Sec12 and is mapped to human chromosome 2p23. The encoded 417 amino acids protein contains highly conserved seven WD-40 folds. It is localized to the ER (endoplasmic reticulum) exit sites in mammalian cells. The encoded protein contains two PQ-rich potential transactivation domains and lacks a DNA binding motif. This gene overlaps the αβhydrolase domain containing 1 (ABHD1) gene along a stretch of 42bp and may be associated with some of the developmental abnormalities found in patients with partial trisomy 2p.