Merck Anti-Vinculin antibody produced in rabbit

Anti-Vinculin antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

생물학적 소스

rabbit

Quality Level

200

결합

unconjugated

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

antigen ~116 kDa

species reactivity

mouse, human, rat

향상된 검증

independent
Learn more about Antibody Enhanced Validation

technique(s)

indirect immunofluorescence: 15-30 μg/mL using acetone-fixed frozen sections of rat or human heart
western blot: 2.5-5 μg/mL using whole extracts of cultured mouse NIH3T3 cells and human hepatoma HepG2 cells

UniProt 수납 번호

P18206

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... VCL(7414)
mouse ... Vcl(22330)
rat ... Vcl(305679)

In muscle, vinculin is localized in the fascia adherens of the intercalated disk (cardiac muscle), myotendinous junctions (skeletalmuscle), neuromuscular junctions, and the membrane associated dense bodies of smooth muscle. In many cell types undergoing viral transformation, vinculin becomes redistributed to rosettes or podosomes.