Merck Monoclonal Anti-β-Tubulin antibody produced in mouse

Monoclonal Anti-β-Tubulin antibody produced in mouse

clone TUB 2.1, ascites fluid

Quality Level

200

생물학적 소스

mouse

결합

unconjugated

항체 형태

ascites fluid

antibody product type

primary antibodies

클론

TUB 2.1, monoclonal

분자량

antigen 55 kDa

포함

15 mM sodium azide

species reactivity

wheat, mouse, hamster, sea urchin, frog, plant, bovine, rat, rabbit, moth, chicken, human

향상된 검증

independent ( Antibodies)
Learn more about Antibody Enhanced Validation

technique(s)

indirect immunofluorescence: 1:200 using cultured chicken fibroblasts
western blot: 1:100 using human or chicken fibroblast cell extract

동형

IgG1

application(s)

research pathology

배송 상태

dry ice

저장 온도

−20°C

β-Tubulin belongs to the subfamily of tubulin, which is the major building block of microtubules. β-Tubulin has a molecular weight of 55kDa. β-Tubulin structure is characterized with core of two β-sheets enclosed by α-helices. It also contains an N-terminal domain with the guanine nucleotide-binding region, an intermediate domain with taxol-binding site, and a C-terminal domain that contains the binding surface for molecular motor proteins. Human β-tubulin consists of seven isoforms (βI (class I), βII (class II), βIII (class III), βIVa (class IVa), βIVb (class IVb), βV (class V), and βVI (class VI)).
Monoclonal Anti-b-Tubulin (mouse IgG1 isotype) is derived from the hybridoma TUB 2.1 produced by the fusion of mouse myeloma cells and splenocytes from a mouse immunized with purified rat brain tubulin.