Merck Neuraminidase (Sialidase)

Neuraminidase (Sialidase)

from Vibrio cholerae

Salidase

Quality Level

100

form

solution

specific activity

~20 units/mg protein (Approximately 40 U/mg enzyme protein at 37 °C and pH 5.5, with N-acetyl-neuraminosyl-D-lactose as the substrate.)

분자량

~95 kDa

포장

pkg of 1 U

manufacturer/tradename

Roche

최적 pH

5.5-6.2

배송 상태

wet ice

저장 온도

2-8°C

Neuraminidase is an acylneuraminyl hydrolase which hydrolyzes terminal N- or O-acylneuraminic acids which are α2,3-, α2,6-, or α2,8-linked (rate: α2,6 > α2,3 > α2,8) to oligosaccharides, polysaccharides, mucopolysaccharides, glycoproteins, and glycolipids. Noteworthy, for the hydrolysis of glycolipids, the presence of a detergent is necessary. Because of the broad substrate specificity, the enzyme is very well suited for the complete removal of sialic acids from glycoconjugates of a wide variety of biological materials (e.g., in cytology, on cell surfaces, viruses etc.).