Merck IL-1β human

IL-1β human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

Leukocyte endogenous mediator (LEM), Lymphocyte-activating factor (LAF), Catabolin, Mononuclear cell factor (MCF), Endogenous pyrogen (EP)

생물학적 소스

human

재조합

expressed in HEK 293 cells

assay

≥95% (SDS-PAGE)

form

lyophilized

분자량

(18 and 25 kDa, monomer, glycosylated)

포장

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

NCBI 수납 번호

P01584

배송 상태

dry ice

저장 온도

−70°C

Gene Information

human ... IL1B(3553)

Interleukin-1β (IL1B) is produced by activated macrophages. It is synthesized as pro-IL-1β which is changed to active form IL-1β with the help of pro-inflammatory protease caspase-1. IL-1β belongs to the IL-1 gene family. It is a proinflammatory cytokine. The gene is mapped to human chromosome 2q14. In comparison with the Escherichia coli expressed protein, IL-1β is 50% more potent in promoting human CD4+ T cell differentiation into Th17 (T helper) cells. This cytokine is produced in a serum free, chemically defined media.