Merck VEGF-B human

VEGF-B human

recombinant, expressed in E. coli

VEGFB, Vascular Endothelial Growth Factor-B

생물학적 소스

human

재조합

expressed in E. coli

assay

≥98% (SDS-PAGE)

form

lyophilized

효능

0.5-5.0 μg/mL

분자량

~19.63 kDa

포장

pkg of 20 μg

저장 조건

avoid repeated freeze/thaw cycles

불순물

endotoxin, tested

NCBI 수납 번호

P49765

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... VEGFB(7423)

Vascular endothelial growth factor B (VEGF-B), a member of the VEGF family, is a potent growth and angiogenic cytokine. VEGF-B is expressed in all tissues except the liver. It forms cell surface-associated disulfide linked homodimers and can form heterodimers with VEGF-A. There are two known isoforms, formed by alternative splicing, which have been designated VEGF-B167 and VEGF-B186. Both forms have identical amino-terminal sequences encoding a cysteine knot like structural motif, but differ in their carboxyl-terminal domains. Both VEGF-B isoforms signal only through the VEGFR1 receptor. The gene encoding this protein is localized on human chromosome 11q13 and contains seven exons. Recombinant human VEGF-B is a 38kDa disulfide-linked homodimeric protein consisting of two 167 amino acid polypeptide chains.