Merck BMP-4 Protein, Human Recombinant

BMP-4 Protein, Human Recombinant

The Bone morphogenetic protein 4 (or BMP-4 protein) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood.

BMP4, Bone morphogentic protein-4, DVR-4

Quality Level

100

assay

>97% (SDS-PAGE and HPLC)

불순물

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI 수납 번호

NM_001202.3
NM_130850.2
NM_130851.2

UniProt 수납 번호

P12644

배송 상태

dry ice

Bone morphogentic protein 4 (BMP-4) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.