Merck Interleukin-1β from rat

Interleukin-1β from rat

IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Lymphocyte activating factor, IL-1β, Interleukin-1β from rat

Quality Level

100

생물학적 소스

rat

재조합

expressed in E. coli

assay

≥98% (SDS-PAGE and HPLC)

form

lyophilized powder

효능

0.01-0.1 ng/mL ED50/EC50

분자량

17.3 kDa

포장

pkg of 10 and 50 μg

technique(s)

cell culture | mammalian: suitable

불순물

<0.1 EU/μg

UniProt 수납 번호

Q63264

저장 온도

−20°C

Gene Information

rat ... Il1b(24494)

Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin-2.1 IL-1 is primarily released from stimulated macrophages and monocytes, but is also released from several other cell types,2 and is thought to play a key role in inflammatory and immune responses.3 Other synonyms for IL-1 include: Endogenous Pyrogen (EP), Mitogenic Protein (MP), Helper Peak-1 (HP-1), T Cell Replacing Factor III (TRF III or TRFH), B cell Activating Factor (BAF) and B Cell Differentiation Factor (BDF).4 The two closely related agents, Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) bind to the same cell surface receptor, elicit nearly identical biological responses and yet share 25% homology in their amino acid sequence. Recombinant rat IL-1β is a 17.3 kDa protein containing 153 amino acid residues.