Merck IL-7 human
Recombinant human IL-7, animal-component free, expressed in E. coli. ≥98% purity (HPLC, SDS-PAGE). Supports lymphocyte development and B cell precursor growth. Supplied lyophilized, 10 μg pack, stored at −20°C.
- 카탈로그번호
- SRP3266-10UG
- 브랜드
- Merck Sigma
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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IL-7 human
제품 개요
Animal-component free recombinant human IL-7, expressed in E. coli, with ≥98% purity by SDS-PAGE and HPLC. Also known as Lymphopoietin 1 (LP-1) or pre-B cell factor.
제품 설명
IL7 (interleukin 7) was first identified in 1988 in a bone marrow culture as a factor that facilitated murine B cell precursor growth. It is a cytokine produced by non-lymphoid cells in lymphoid organs.
In humans, it is also produced by keratinocytes, peripheral blood dendritic cells, follicular dendritic cells, intestinal epithelial cells, hepatic tissue, endothelial cells, smooth muscle cells, and fibroblasts.
The IL7 gene is localized to human chromosome 8q12–q13. It is a glycoprotein with a four α-helix structure and a hydrophobic core. Recombinant human IL-7 is a 17.4 kDa protein containing 153 amino acid residues.
제품 사양
| 항목 | 내용 |
|---|---|
| 생물학적 소스 | Human |
| 발현 시스템 | E. coli |
| 형태 | Lyophilized |
| 순도 | ≥98% (HPLC), ≥98% (SDS-PAGE) |
| 효능 (ED₅₀) | ≤0.5 ng/mL |
| 분자량 | 17.4 kDa |
| 포장 단위 | 10 μg |
| 불순물 | <0.1 EU/μg endotoxin, tested |
| 색상 | White to off-white |
| UniProt 번호 | P13232 |
| 배송 상태 | Wet ice |
| 저장 온도 | −20 °C |
| 관련 유전자 | IL7 (3574) |
참고 정보
- Lymphopoietin 1 (LP-1), pre-B cell factor로도 알려져 있음
- 면역세포 성장 및 분화 조절에 중요한 역할 수행
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