Merck Interleukin-23 human
Recombinant human Interleukin-23 (IL-23) produced in HEK 293 cells for authentic glycosylation. Suitable for mammalian cell culture. High purity (≥95%) lyophilized powder form. Endotoxin tested and biologically active cytokine for immunological studies.
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Interleukin-23 Human (HumanKine®)
Recombinant human IL-23 expressed in HEK 293 cells, suitable for mammalian cell culture applications.
제품 설명
HumanKine Interleukin-23 (IL-23) is a heterodimeric 55 kDa cytokine composed of two glycosylated and disulfide-linked subunits (p40 cystine linked to p19). Production in human HEK 293 cells ensures authentic human-like glycosylation.
Cytokines produced in insect cells (Sf_9 or _Sf_21) may exhibit non-human post-translational modifications.
Interleukin-23 (IL-23) is a pro-inflammatory cytokine primarily synthesized by activated dendritic cells and macrophages. It is a 20.7 kDa protein consisting of 189 amino acids, expressed mainly on activated/memory T cells and natural killer (NK) cells. The IL23A gene is located on human chromosome 12q13.3.
제품 사양
| 항목 | 내용 |
|---|---|
| 생물학적 소스 | Human |
| 재조합 발현 | HEK 293 cells |
| 품질 등급 | 100 |
| 형태 | Lyophilized powder |
| 순도 (assay) | ≥95% (SDS-PAGE) |
| 효능 (EC50) | ≤2 ng/mL |
| 품질 시험 | Endotoxin tested |
| 분자량 | Dimer 55 kDa (glycosylated) |
| 불순물 | ≤1 EU/mg |
| 포장 단위 | pkg of 5×10 μg / pkg of 10 μg / pkg of 5 μg |
| 적용 기술 | Cell culture (mammalian, suitable) |
| UniProt 번호 | Q9NPF7 |
| 저장 온도 | −20°C |
| 유전자 정보 | Human IL23A (51561) |
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