Merck BDNF human

BDNF human

Carrier free, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), suitable for cell culture

Brain Derived Neurotrophic Factor

생물학적 소스

human

재조합

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

lyophilized

효능

≤15 ng/mL ED50

분자량

27.0 kDa

포장

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

불순물

≤1.00 EU/μg endotoxin, tested

UniProt 수납 번호

P23560

배송 상태

wet ice

저장 온도

−20°C

Gene Information

human ... BDNF(627)

The gene BDNF (brain derived neurotrophic factor) is mapped to human chromosome 11p14.1. BDNF is a member of the neurotrophin family of growth factors. The gene encodes a precursor protein, proBDNF. Mature BDNF (mBDNF) is synthesized by post-translational cleavage of proBDNF. Both proBDNF and mBDNF play crucial roles in cellular signaling. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0kDa homodimer of two 119 amino acid subunits linked by strong noncovalent interactions.