Merck Complement C7 deficient serum human

Complement C7 deficient serum human

for complement assays

Quality Level

200

생물학적 소스

human

form

solution

technique(s)

activity assay: suitable

UniProt 수납 번호

P10643

배송 상태

dry ice

저장 온도

−70°C

Gene Information

human ... C7(730)

Complement C7 deficiencies in humans are rare, but often associated with recurrent infections by Neisseria spp. (such as meningitis). C7 deficiencies in patients with meningococcal meningitis have shown a mutation which results in an 11 bp deletion in exon 6 resulting in a premature stop codon. Additionally, research has suggested that screening of patients with systemic neisserial infection by CH50 or the APH-50 assay can reveal a C7 deficiency.