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Thermo Fisher Scientific CD33 Monoclonal Antibody (WM53), PerCP

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CD33 단백질을 인식하는 WM53 클론의 마우스 모노클로날 항체로, PerCP로 결합되어 유세포분석(Flow Cytometry)에 적합합니다. 인간 및 비인간 영장류 반응성이 있으며, 4°C 암소 보관이 권장됩니다. 연구용으로만 사용 가능합니다.

카탈로그번호: A15804
브랜드: Thermo Fisher Scientific
카테고리: Monoclonal Antibodies
판매단위: pk

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마지막 업데이트 2025. 08. 01. 오후 10:47

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Thermo Fisher Scientific A15804 CD33 Monoclonal Antibody (WM53), PerCP 100 tests pk판매 단위 pk ·

재고 확인 필요재고 확인 필요

354,900원VAT 포함 390,390원

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Thermo Fisher Scientific · Thermo Fisher Scientific CD33 Monoclonal Antibody (WM53), PerCP

Applications

Flow Cytometry (Flow): 10 µL/1×10⁶ cells

Product Specifications

항목	내용
Species Reactivity	Human, Non-human primate
Host / Isotype	Mouse / IgG1
Class	Monoclonal
Type	Antibody
Clone	WM53
Immunogen	Human AML cells
Conjugate	PerCP
Excitation / Emission Max	482 / 675 nm
Form	Liquid
Purification	Size-exclusion chromatography
Storage Buffer	PBS with 0.2% BSA
Contains	15 mM sodium azide
Storage Conditions	4°C, store in dark, DO NOT FREEZE
Shipping Conditions	Ambient (domestic); Wet ice (international)
RRID	AB_2534580

Additional Formats

Product Specific Information

This antibody reacts with an extracellular epitope of CD33, a 67 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells, and mast cells. It is absent on platelets, lymphocytes, erythrocytes, and hematopoietic stem cells.

Target Information

CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that recruit protein tyrosine phosphatases SHP-1 and SHP-2, mediating inhibitory signaling and receptor internalization. CD33 is expressed on cells of the myelomonocytic lineage, binds sialic acid residues on cell surface glycans, and serves as a therapeutic target for acute myeloid leukemia. It is present on granulocyte and macrophage precursors in bone marrow but not on pluripotent stem cells, and is a useful marker for peripheral monocytes. CD33 helps distinguish myelogenous leukemia from lymphoid or erythroid leukemias. Diseases associated with CD33 dysfunction include gallbladder lymphoma and extracutaneous mastocytoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.