Thermo Fisher Scientific CACNA1I Polyclonal Antibody
CACNA1I 단백질을 인식하는 토끼 폴리클로날 항체로, 인간 시료에 반응합니다. ICC/IF 실험에 적합하며, 정제된 액상 형태로 제공됩니다. 항원은 PrEST 재조합 단백질 서열 기반이며, 단백질 발현 및 신경세포 칼슘 채널 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 1842–1934). Recombinant protein control fragment: RP-110066 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3091888 |
Product Specific Information
Immunogen sequence:
HHDKQEVQLA ETEAFSLNSD RSSSILLGDD LSLEDPTACP PGRKDSKGEL DPPEPMRVGD LGECFFPLSS TAVSPDPENF LCEMEEIPFN PVR
Antigen sequence identity:
- Mouse: 78%
- Rat: 26%
Target Information
CaV3.3 encodes the pore-forming alpha subunit of a voltage-gated calcium channel. This protein is a member of the low voltage-activated, T-type calcium channel subfamily. CaV3.3 channels activate and inactivate more slowly than other T-type channels and may participate in neuronal calcium signaling.
Voltage-gated calcium channels (CaV) mediate calcium influx in response to depolarization and regulate processes such as contraction, secretion, neurotransmission, and gene expression.
Diseases associated with CACNA1I include Childhood Absence Epilepsy.
Alternate splicing results in multiple transcript variants of CaV3.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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