Thermo Fisher Scientific TFEB Polyclonal Antibody
TFEB 단백질을 표적하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, WB 및 ICC/IF에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태이며 안정적인 저장 조건 제공합니다. 인간 TFEB 단백질에 높은 특이성과 재현성을 보입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 82–141). Recombinant protein control fragment (Product #RP-110210). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092339 |
Product Specific Information
- Immunogen sequence:
YHLQQSQHQK VREYLSETYG NKFAAHISPA QGSPKPPPAA SPGVRAGHVL SSSAGNSAPN - Antigen sequence identity: Mouse 95%; Rat 97%
Target Information
Transcription factor EB (TFEB) is a member of the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors.
Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1.
Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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