Thermo Fisher Scientific Phospho-Cdc25C (Thr48) Polyclonal Antibody
Cdc25C 단백질의 Thr48 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. 세포 분열 조절 연구에 적합하며, 인간 시료에 검증됨. 액상 형태, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CDC25C around the phosphorylation site of Thr48 (P-R-TP-P-V) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2554959 |
Target Information
M-phase inducer phosphatase 3 is an enzyme encoded by the CDC25C gene in humans. This gene is highly conserved and plays a key role in regulating cell division. The encoded protein is a tyrosine phosphatase belonging to the Cdc25 phosphatase family. It dephosphorylates cyclin B-bound CDC2 (CDK1), triggering entry into mitosis, and is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants have been described, though the full-length nature of many is not known.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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