Thermo Fisher Scientific RTEL1 Polyclonal Antibody
RTEL1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 RTEL1에 반응하며, ICC/IF 실험에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보존.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RTEL1. Recombinant protein control fragment (Product #RP-105423) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664991 |
Product Specific Information
Immunogen sequence:
PKKHNLLQGFY QFVRPHHKQQ FEEVCIQLTG RGCGYRPEHS IPRRQRAQPV LDPTGRTAPD PKLTVSTAAA QQLDPQEHLN QG
Highest antigen sequence identity to the following orthologs:
- Mouse: 53%
- Rat: 60%
Target Information
ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair, and maintenance of genomic stability.
Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis.
Regulates meiotic recombination and crossover homeostasis by dissociating strand invasion events, promoting noncrossover repair via SDSA, and disassembling D-loop intermediates.
Also disassembles T-loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, ensuring telomere dynamics and stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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