Thermo Fisher Scientific HOMER3 Polyclonal Antibody
HOMER3 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC 등 다양한 응용에 사용 가능. 인간에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS와 글리세롤 버퍼에 보관되며 연구용으로 적합.
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- PA559383
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 | – |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | View 1 publication |
| Flow Cytometry (Flow) | – | View 1 publication |
| Immunoprecipitation (IP) | – | View 1 publication |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HOMER3. Recombinant protein control fragment (Product # RP-98314) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642508 |
Product Specific Information
Immunogen sequence:
ALVQTKDQEI QTLKSQTGGP REALEAAERE ETQQKVQDLE TRNAELEHQL RAMERSLEEA RAERERARAE VGRAAQLLDV RLFELSELRE GL
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 88%
Target Information
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors, and amyloid precursor proteins, and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation, and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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