Thermo Fisher Scientific MHC Class II (I-A/I-E) Monoclonal Antibody (CIa)
닭 MHC Class II 분자(I-A/I-E)를 인식하는 Mouse IgM 단클론 항체로, Flow Cytometry에 사용 가능. 비결합형(Unconjugated) 형태이며, 0.5 mg/mL 농도로 제공. 항원제시세포 연구 및 면역펩티돔 분석에 적합.
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Thermo Fisher Scientific MHC Class II (I-A/I-E) Monoclonal Antibody (Clone: CIa)
Applications
- Flow Cytometry (Flow): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Avian, Chicken |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CIa |
| Immunogen | Splenic leukocytes from an outbred nine-week-old chicken |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2, with proprietary stabilizer |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745769 |
Additional Formats
Target Information
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on professional antigen-presenting cells such as macrophages, dendritic cells, and B cells. Before being displayed on the cell surface, MHC class II molecules bind endocytosed exogenous antigens, which are then presented to T cells.
The antigen-binding groove between MHC class II alpha and beta chains is open at both ends and typically accommodates peptides 15–24 amino acids long.
HLA and MHC antibodies play a critical role in immunopeptidomics, enabling identification and characterization of neoantigens via high-performance liquid chromatography coupled with tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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