Thermo Fisher Scientific RGMB Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.1 µg/mL

Flow Cytometry (Flow)

• Tested Dilution: 0.25 µg per million cells

Product Specifications

Product Specific Information

In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant mouse RGM-B is observed and less than 1% cross-reactivity with recombinant human (rh) RGM-A and rhRGM-C is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.