
Thermo Fisher Scientific APPL1 Recombinant Rabbit Monoclonal Antibody (23GB1570)
APPL1 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. 세포 증식 및 인슐린 신호 전달 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB1570 |
| Immunogen | A synthesized peptide derived from human APPL (400–450AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The protein encoded by this gene is involved in the regulation of cell proliferation and mediates crosstalk between adiponectin and insulin signaling pathways. It interacts with proteins such as RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and NuRD/MeCP1 complex components. This protein is associated with endosomal membranes but can be released by EGF stimulation and translocated to the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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