Thermo Fisher Scientific EDG8 Polyclonal Antibody
EDG8 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC에 사용 가능. Human 및 Mouse 시료에 반응하며, 고순도의 affinity chromatography 정제 제품. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human S1PR5 (Accession Q9H228), corresponding to amino acid residues A341–L391. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850426 |
Product Specific Information
This antibody detects endogenous levels of total EDG8.
Target Information
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may occur both intracellularly as a second messenger and extracellularly as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal through G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors, while others (e.g., EDG2) are LPA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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