Thermo Fisher Scientific ABCB9 Polyclonal Antibody
ABCB9 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot에 적합합니다. N-말단 합성 펩타이드로 면역화되었으며, 다양한 종에 반응합니다. 고순도 친화 크로마토그래피 정제 제품으로, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human ABCB9 (aa 2–51) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2577126 |
Product Specific Information
Peptide sequence:
RLWKAVVVTL AFMSVDICVT TAIYVFSHLD RSLLEDIRHF NIFDSVLDLW
Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 75%
Human: 100%
Mouse: 100%
Pig: 93%
Rabbit: 93%
Rat: 100%
Target Information
The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of DNA lesions:
- NER (Nucleotide Excision Repair) for UV-induced lesions and bulky chemical adducts
- Recombination Repair for genotoxic interstrand crosslinks
NER involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells, XPG cleaves 3′ of the DNA lesion, while the ERCC1/XPF complex makes the 5′ incision. ERCC1/XPF likely plays a role in processing partially processed recombination intermediates.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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