Thermo Fisher Scientific ANKMY2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human ANKMY2. Recombinant protein control fragment (Product #RP-92679). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ANKMY2,uniProtId:Q8IV38-1,ncbiNodeId:9606,antigenRange:240-331,antigenLength:441,antigenImageFileName:PA5-111207_ANKMY2_Q8IV38-1_Rabbit.svg,antigenImageFileNamePDP:PA5-111207_ANKMY2_Q8IV38-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856617

Product Specific Information

Immunogen sequence: ENKLDTLIKS LLKGRASDGF PVYQEKIIRE SIRKFPYCEA TLLQQLVRSI APVEIGSDPT AFSVLTQAIT GQVGFVDVEF CTTCGEKGAS KR

Target Information

ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.