LanthaScreen™ Tb-pMAP2K1 (pSer217/221) Antibody Kit

A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range자세히 알아보기

A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf. For use in combination with the Fluorescein-MAP2K1 physiological protein substrate (PV4812) to evaluate inhibitors in medium to high throughput screening applications.

사양

애플리케이션Kinase Assay, Enzyme and Protein Activity Assays, Kinase Assay

콘주게이트Tb (Terbium)/FITC/Lanthanide Chelates

유전자 별칭COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, CRAF,NS5,Raf-1,c-Ra, MEKK9,MLK1,PRKE, COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, MEKK7,TAK1,TGF1, MEKK9,MLK1,PRKE, ASK1,MAPKKK5,MEKK, MEKK10,MLK2,MS, MEKK11,MGC17114,MLK-3,MLK3,PTK1,SPR, CRAF,NS5,Raf-1,c-Ra,

항원의 분자량150kDa

수량25 μg

인허가 상태RUO, RUO

연구 영역Target and Lead Identification and Validation

일차 또는 이차Primary

유전자 ID(Entrez)10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885

포장1 Kit(s)

포함0.02% Sodium azide

항체 분자량150000 Da

어세이 입력Biochemical terbium phospho-specific activity

형식384-well Plate

여기/방출340⁄490, 520

반응성Human

배송 조건Dry Ice

판독End Point

반응성 약어Hu

타겟 입력MAP3K2, RAF1 (cRAF) Y340D Y341D, MAP3K10, MAP3K9, MAP3K7/MAP3K7IP1, MAP3K5, MAP3K11, BRAF V599E, BRAF, MAP3K8, MAP3K3

타겟 효소Serine⁄Threonine Kinases

기술TR-FRET

검증된 키나아제BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11

Unit SizeEach