Thermo Fisher Scientific APOC4 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 100% as determined by SDS-PAGE.

Target Information

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which modulate the metabolism of triglyceride-rich lipoproteins.

• The human apoC-I gene maps to chromosome 19q13.2 and is primarily expressed in the liver, activated when monocytes differentiate into macrophages.
• The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single-chain protein that acts as a cofactor for lipoprotein lipase activation.
• The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase.
• The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein primarily expressed in the liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.