Thermo Fisher Scientific ERO1LB Polyclonal Antibody
Thermo Fisher Scientific의 ERO1LB Polyclonal Antibody는 인간 ERO1LB 단백질을 인식하는 토끼 유래 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer와 glycerol로 안정화되어 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ERO1LB. Recombinant protein control fragment (Product # RP-94044) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641117 |
Product Specific Information
Immunogen sequence:
NLKRPCPFWA EDGHCSIKDC HVEPCPESKI PVGIKAGHSN KYLKMANNTK ELEDCEQANK LGAINSTLSN QSKEAFIDWA RYDDSRDHFC ELDDE
Highest antigen sequence identity:
- Mouse: 92%
- Rat: 93%
Target Information
ERO1LB is an essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. It acts by oxidizing directly P4HB/PDI isomerase through a disulfide exchange mechanism. ERO1LB does not act as a direct oxidant of folding substrates but relies on P4HB/PDI to transfer oxidizing equivalents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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