Thermo Fisher Scientific CFHR1 Polyclonal Antibody
Thermo Fisher Scientific CFHR1 Polyclonal Antibody는 인간 CFHR1 단백질을 검출하기 위한 토끼 IgG 항체로, WB, IHC, ELISA에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 안정적인 액상 형태로 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1:2,000–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to a region derived from 22–330 amino acids of human complement factor H-related 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2635157 |
Product Specific Information
This antibody detects endogenous levels of total CFHR1 protein.
Target Information
The CFHR1 gene encodes a secreted protein belonging to the complement factor H family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. Tuf acts as a virulence factor by acquiring host proteins on the pathogen surface, controlling complement activity, and facilitating tissue invasion. Mutations in CFHR1 are associated with increased risk of atypical hemolytic-uremic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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