Thermo Fisher Scientific MRE11 Polyclonal Antibody
MRE11 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, IP 등 다양한 응용에 적합함. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. DNA 손상 복구 연구에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MRE11 Polyclonal Antibody
Thermo Fisher Scientific MRE11 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 132–572 of Human MRE11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548736 |
Product Specific Information
- Recommended positive controls: HeLa, A431, C8D30, NIH-3T3, PC-12
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex, which plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity, and meiosis.
The complex possesses single-stranded endonuclease activity and double-strand-specific 3′–5′ exonuclease activity provided by MRE11. RAD50 is required to bind DNA ends and hold them in close proximity.
Mutations in the MRE11 gene can result in ataxia-telangiectasia-like disorder 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.