Thermo Fisher Scientific UBXN2B Monoclonal Antibody (OTI2E8)
UBXN2B 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, ICC/IF, Flow Cytometry에 사용 가능. 인간, 개, 비인간 영장류 반응성. 액상 형태로 0.75 mg/mL 농도, PBS/BSA/glycerol 버퍼에 보관. ER 및 골지체 생합성과 유지 연구에 적합.
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Thermo Fisher Scientific UBXN2B Monoclonal Antibody (OTI2E8)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E8 |
| Immunogen | Full length human recombinant protein of UBXN2B produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723763 |
Target Information
UBXN2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein containing one UBX domain and one SEP domain.
UBXN2B is required for ER and Golgi biogenesis and plays a role in their maintenance during interphase and reassembly at the end of mitosis.
Through interaction with VCP, UBXN2B forms a complex with membrane fusion activity.
Adapter protein required for Golgi and endoplasmic reticulum biogenesis, maintenance, and reassembly.
The complex with VCP requires USO1-GOLGA2 tethering and BET1L; VCPIP1 is also required, though not its deubiquitinating activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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