Thermo Fisher Scientific FHOD3 Polyclonal Antibody
Human FHOD3 단백질에 특이적인 Rabbit Polyclonal 항체로, IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼(40% glycerol, 0.02% sodium azide) 내 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FHOD3. Recombinant protein control fragment (Product # RP-88593). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641622 |
Product Specific Information
Immunogen sequence:
GVDTELLVYA MTLVNKTLSG LPDQDTFYDV VDCLEELGIA AVSQRHLNKK
GTDLDLVEQL NIYEVALRHE DGDETTEPPP SGCRDRRRAS VCSSGGGEHR
GLDRRRSRRH SVQSIKSTLS APTSPCSQSA PSFKPNQV- Highest antigen sequence identity to the following orthologs:
- Mouse: 87%
- Rat: 87%
Target Information
FHOD3 is a novel member of the formin homology family playing an important role in the regulation of the actin cytoskeleton. It contains several key domains:
- DAD (diaphanous auto regulatory) domain
- FH1 (formin homology 1) domain
- FH2 (formin homology 2) domain
- GBD/FH3 (Rho GTPase-binding/formin homology 3) domain
FHOD3 is a cytoplasmic protein that mainly localizes to actin fibers, with partial filamentous staining. It is a 1422 amino acid formin-related actin-organizing protein that may induce stress fiber formation and cell elongation, possibly associating with nestin/NES-based intermediate filaments (IF). Expression is observed mainly in the heart, kidney, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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