Thermo Fisher Scientific FHOD3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FHOD3. Recombinant protein control fragment (Product #RP-88593). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FHOD3,uniProtId:Q2V2M9-1,ncbiNodeId:9606,antigenRange:256-393,antigenLength:1422,antigenImageFileName:PA5-54524_FHOD3_Q2V2M9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54524_FHOD3_Q2V2M9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641622

Product Specific Information

Immunogen sequence: GVDTELLVYA MTLVNKTLSG LPDQDTFYDV VDCLEELGIA AVSQRHLNKK GTDLDLVEQL NIYEVALRHE DGDETTEPPP SGCRDRRRAS VCSSGGGEHR GLDRRRSRRH SVQSIKSTLS APTSPCSQSA PSFKPNQV

Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.

Target Information

FHOD3 is a novel member of the formin homology family playing an important role in regulation of the actin cytoskeleton. It contains a DAD (diaphanous auto regulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. FHOD3 is a cytoplasmic protein where the main part of the protein localizes to actin fibers and the remaining part displays filamentous staining. A 1422 amino acid containing formin-related actin-organizing protein, FHOD3 may cause stress fiber formation together with cell elongation and may associate with nestin/NES-based interfilament (IF). Expression of FHOD3 is seen mainly in heart, kidney, and brain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.