Thermo Fisher Scientific EBP1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human EBP1 protein, suitable for WB, IHC, and IP applications. Recognizes residues 300–345 of ErbB-3 Binding Protein 1. Supplied as unconjugated liquid form, 0.20 mg/mL concentration, stored at 4°C. For research use...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 300 and 345 of human ErbB-3 Binding Protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
Target Information
This gene encodes an RNA-binding protein involved in growth regulation. It is present in pre-ribosomal ribonucleoprotein complexes and may participate in ribosome assembly and rRNA processing. EBP1 interacts with the cytoplasmic domain of the ErbB3 receptor and contributes to growth regulatory signal transduction. Additionally, it functions as a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through interactions with histone deacetylases. EBP1 has been implicated in growth inhibition and differentiation induction of human cancer cells. Six pseudogenes have been identified on chromosomes 3, 6, 9, 18, 20, and X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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