Thermo Fisher Scientific GTF2H2 Polyclonal Antibody
GTF2H2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 사용 가능. 인간, 마우스, 랫트 반응성. 액상 형태, 1 mg/mL 농도, -20°C 보관.
- 카탈로그번호
- PA5104234
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GTF2H2 (Accession Q13888), corresponding to amino acid residues M1–E48 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853558 |
Product Specific Information
Antibody detects endogenous levels of total TF2H2.
Target Information
Initiation of transcription from protein-coding genes in eukaryotes requires RNA polymerase II and multiple basal transcription factors. The factor TFIID (TBP) binds to the TATA box to initiate formation of a multiprotein complex including TFIIA, TFIIB, TFIIE, TFIIF, and TFIIH.
TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor with several enzymatic activities. The core of TFIIH consists of five subunits: p89 (XPB or ERCC3), p62, p52, p44, and p34. Additional subunits include p80 (XPD or ERCC2) and the ternary kinase complex (Cdk7, cyclin H, MAT1). Both p89 and p80 exhibit ATP-dependent helicase activity, while p62, p52, and p44 are involved in nucleotide excision repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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