Thermo Fisher Scientific CDKN2C Polyclonal Antibody
CDKN2C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능. Affinity chromatography로 정제된 고순도 항체로, 인간 및 생쥐 시료에 반응. 연구용으로만 사용.
- 카탈로그번호
- PA5104235
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CDKN2C (Accession P42773), corresponding to amino acid residues L122–Q168 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853559 |
Product Specific Information
Antibody detects endogenous levels of total p18 INK4c.
Target Information
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. It interacts with CDK4 or CDK6 and prevents activation of CDK kinases, functioning as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression suppresses human cell growth, correlating with wild-type RB1 function. Knockout mouse studies suggest roles in spermatogenesis and tumorigenesis suppression. Two alternatively spliced transcript variants encoding identical proteins have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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