Thermo Fisher Scientific beta-2 Adrenergic Receptor Polyclonal Antibody
Human β2 Adrenergic Receptor 인식하는 Goat Polyclonal Antibody로, Western Blot에 최적화됨. 합성 펩타이드 면역원 사용. 액상 형태로 0.5 mg/mL 농도. -20°C 보관, sodium azide 포함. 연구용 전용 시약.
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- PA518423
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (HQGTVPSDNIDSQ) corresponding to the C-terminus amino acids of ADRB2 (aa 390–403) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10988357 |
Product Specific Information
- This antibody is predicted to react with canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind endogenous catecholamines epinephrine and norepinephrine.
Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family.
Nine receptor subtypes have been identified thus far, including:
- Three alpha-1 AR subtypes (1A/D, 1B, and 1C)
- Three alpha-2 ARs (2A, 2B, and 2C)
- Three beta AR subtypes (1, 2, and 3)
ARs participate in the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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