Thermo Fisher Scientific CHRM1 Polyclonal Antibody
CHRM1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 IHC에 사용 가능하며 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며, 재구성 후 -20°C에서 보관합니다.
- 카탈로그번호
- AMR-001-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CHRM1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | GST fusion protein with sequence corresponding to amino acid residues 227–353 of human M1 (3rd intracellular loop) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.95 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunogen sequence:
GSETPGKGGG SSSSSERSQP GAEGSPETPP GRCCRCCRAP RLLQAYSWKE EEEEDEGSME SLTSSEGEEP GSEVVIKMPM VDPEAQAPTK QPPRSSPNTV KRPTKKGRDR AGKGQKPRGK EQLAKRK
Reconstitution:
Reconstitute with 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW) depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and store at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Muscarinic cholinergic receptors belong to the G protein-coupled receptor family. Their functional diversity is defined by acetylcholine binding, leading to cellular responses such as adenylate cyclase inhibition, phosphoinositide degradation, and potassium channel mediation.
These receptors influence many acetylcholine-mediated effects in the central and peripheral nervous systems.
Muscarinic cholinergic receptor 1 (CHRM1) is involved in vagally induced bronchoconstriction and gastric acid secretion.
The CHRM1 gene is localized to chromosome 11q13.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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