Thermo Fisher Scientific DSCR3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DSCR3. Recombinant protein control fragment (Product #RP-91823). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DSCR3,uniProtId:O14972-1,ncbiNodeId:9606,antigenRange:82-155,antigenLength:297,antigenImageFileName:PA5-54747_DSCR3_O14972-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54747_DSCR3_O14972-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640802

Product Specific Information

Immunogen sequence: GKFPSGKTEI PFEFPLHLKG NKVLYETYHG VFVNIQYTLR CDMKRSLLAK DLTKTCEFIV HSAPQKGKFT PSPV

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

Target Information

The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.