Thermo Fisher Scientific Arylsulfatase G Polyclonal Antibody
Human Arylsulfatase G에 특이적인 Rabbit Polyclonal Antibody로 IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 단백질 발현 연구 및 세포 내 위치 분석에 적합.
- 카탈로그번호
- PA554746
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Arylsulfatase G. Recombinant protein control fragment (Product #RP-93288) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638260 |
Product Specific Information
Immunogen sequence:
RVPVNVTSTA LLSVLDIFPT VVALAQASLP QGRHFDGVDV SEVLFGRSQP GHRVLFHPNS GAAGEFGALQ TVR
Antigen sequence identity:
- Mouse: 85%
- Rat: 88%
Target Information
Sulfatases such as ARSG hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules.
This gene encodes a novel arylsulfatase with activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate, which is competitively inhibited by phosphate.
The unprocessed protein is active as a 63-kDa monomer and exhibits an acidic pH optimum typical of lysosomal sulfatases. The protein accumulates within lysosomes and is a glycoprotein that binds specifically to mannose 6-phosphate receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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