Thermo Fisher Scientific alpha Galactosidase Monoclonal Antibody (A7C4)
Human alpha-Galactosidase 단백질을 표적하는 Mouse IgG2b 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. Recombinant protein (aa 51–300/429)을 면역원으로 사용. 2 mg/mL 농도의 액상형 비결합 항체로, Protein A 정제 및 PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:8,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:600
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A7C4 |
| Immunogen | Recombinant protein within human Galactosidase alpha aa 51–300/429 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931424 |
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyzes terminal alpha-galactosyl moieties from glycolipids and glycoproteins.
It predominantly hydrolyzes ceramide trihexoside and can catalyze the hydrolysis of melibiose into galactose and glucose.
Mutations in this gene affect enzyme synthesis, processing, and stability, causing Fabry disease—a rare lysosomal storage disorder resulting from failure to catabolize alpha-D-galactosyl glycolipid moieties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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