Thermo Fisher Scientific IRF4 Polyclonal Antibody
Human IRF4 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. 4°C 단기, -20°C 장기 보관 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IRF4. Recombinant protein control fragment (Product #RP-101901). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789192 |
Product Specific Information
Immunogen sequence:
ALAFSDCRLH ICLYYREILV KELTTSSPEG CRISHGHTYD ASNLDQVLFP YPEDNGQRKN IEKLLSHLER GVVLWMAPDG LYAKRLCQSR IYWDGPLALC NDRPNKLERD QTCKLFDTQQ FLSELQAFAH HGRSLPRFQV TLC
Target Information
The IRF (interferon regulatory factor) family of transcription factors are characterized by a unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to viral infection and in the regulation of interferon-inducible genes.
IRF4 is lymphocyte specific and negatively regulates toll-like receptor (TLR) signaling, which is central to innate and adaptive immune system activation.
A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may cause multiple myeloma. Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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