Thermo Fisher Scientific TFPI Monoclonal Antibody (OTI5A2)
인체 TFPI 단백질을 표적으로 하는 단클론 항체로, Western blot 및 파라핀 조직 면역조직화학에 적합합니다. 고순도 친화 크로마토그래피로 정제되었으며, 안정적인 PBS/BSA/glycerol 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 29–304 of TFPI produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725503 |
Target Information
Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa–TF complex, which activates additional proteases (factors IX and X) and ultimately leads to fibrin clot formation. TFPI inhibits the activated factor X and VIIa–TF proteases in an autoregulatory loop.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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