Thermo Fisher Scientific UGDH Monoclonal Antibody (OTI2C11), TrueMAB
UGDH 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 최적화됨. 사람, 생쥐, 랫트 반응성. 동결건조 형태로 제공되며, PBS 버퍼와 trehalose 함유. 연구용으로 UDP-glucose 대사 관련 단백질 분석에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C11 |
| Immunogen | Full length human recombinant protein of human UGDH produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
UGDH catalyzes the conversion of UDP-glucose to UDP-glucuronate, contributing to the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate.
These compounds are major components of the extracellular matrix and are involved in signal transduction, cell migration, and cancer progression.
Expression is up-regulated by transforming growth factor beta and down-regulated by hypoxia.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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