Thermo Fisher Scientific Influenza A H5N1 HA (A/Common magpie/Hong Kong/2256/2006) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:5,000

ELISA

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Influenza A H5N1 (A/Common magpie/Hong Kong/2256/2006) Hemagglutinin/HA.

Target Information

Influenza A virus is a major public health threat, responsible for more than 30,000 deaths annually in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in Mexico and the United States and subsequently spread worldwide, leading to a pandemic declaration by WHO on June 11, 2009.

Influenza A virus expresses one of sixteen possible Hemagglutinin (HA) and one of nine possible Neuraminidase (NA) surface proteins. Hemagglutinin mediates viral attachment, while Neuraminidase facilitates viral release. These proteins elicit immune responses that can prevent infection or reduce viral replication.

The 2009 H1N1 strain combined genetic elements from human, swine, and avian influenza viruses, with additional genes from Eurasian pig H3N2 viruses. The antigenic differences between this strain and seasonal influenza A (H1N1) suggest limited pre-existing human immunity, though some protection was observed in older populations.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.