
Thermo Fisher Scientific BCAR1 Monoclonal Antibody (OTI1A9), TrueMAB
BCAR1 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC, Flow cytometry에 사용 가능. Human, Mouse, Rat, Dog 반응성. 액상 형태로 제공되며, -20°C에서 보관. 세포 부착 및 신호전달 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A9 |
| Immunogen | Full length human recombinant protein of human BCAR1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.53 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signaling via v-Crk and v-Src oncoproteins. It contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region.
p130Cas is implicated in various biological processes including:
- Cell adhesion and migration
- Growth factor stimulation
- Cytokine receptor engagement
- Bacterial infection
Physiological functions of p130Cas include cardiovascular development, actin filament assembly, and Src-induced cell transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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