Thermo Fisher Scientific ALDH3A1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ALDH3A1, validated for WB and IHC(P) applications. High purity (>95%) and antigen affinity purified. Supplied in liquid form with PBS/glycerol buffer. Designed for research use in oxidative stress and aldehyde...
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Thermo Fisher Scientific ALDH3A1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human ALDH3A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2804004 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in the stomach and even more strongly in the cornea, representing between 5% to 50% of the water-soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by detoxifying reactive aldehydes and directly absorbing UV energy. However, corneas from Aldh3A1⁻ mice are indistinguishable from those of wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 show increased cataract formation following UVB exposure, suggesting that Aldh1A1 may compensate for the loss of Aldh3A1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-87257_ALDH3A1_P30838-1_Rabbit.svg)
(이미지: PA5-87257_ALDH3A1_P30838-1_Rabbit_PDP.jpeg)
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